Accidentally pulled forth into this realm by Bizzaro while performing his trademark eyeball routine, Eyesis is the physical embodiment of the goddess of the Viscous Plane.

It was while feverishly practicing his infamous ocular "dance" that Bizzaro conjured up the eyeball girl. Now in this reality, Eyesis helps Bizzaro to spread his message while avoiding the public eye. She remains mostly a mystery to all.